Consultant in Infection (Oxford University Hospitals NHS Foundation Trust), NIHR Oxford Senior Research Fellow, Oxford Martin School Fellow
I work as a Consultant in infectious diseases and medical microbiology at the John Radcliffe Hospital in Oxford and also run a portfolio of research studies investigating various aspects of: (i) antimicrobial resistance (AMR), particularly in Enterobacterales; (ii) One Health and AMR gene dissemination/pathogen spillover across reservoirs; (iii) rapid diagnostics, including projects on nanoimaging, antigen/antibody tests, and pathogen sequencing, including DNA and RNA sequencing of isolates, and metagenomic sequencing of clinical samples; and (iv) epidemiology of infectious diseases more broadly, including SARS-CoV-2.
I am currently co-supervising four DPhil students and am a member of the Leadership Committee of the Medical Research Foundation's National PhD Training Programme in AMR Research (https://amrtraining.ac.uk/) - a highly interdisciplinary programme specifically designed to incorporate multi-disciplinarity in AMR research.
I am very active in grant and peer review, am on the editorial board of Antimicrobial Agents and Chemotherapy, and support my students in their roles on Microbial Genomics' Early Career Board of Reviewers. I am also strongly supportive of patient and public involvement and engagement (PPIE) in research, having most recently developed a hands-on community programme structured around theatre in educating children and their caregivers about microbes, infections and AMR.
Virus Detection and Identification in Minutes Using Single-Particle Imaging and Deep Learning.
Shiaelis N. et al, (2022), ACS nano
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins
Kuehn R. et al, (2022), Cochrane Database of Systematic Reviews, 2022
Detecting changes in population trends in infection surveillance using community SARS-CoV-2 prevalence as an exemplar
Pritchard E. et al, (2022)
Increasing test specificity without impairing sensitivity: lessons learned from SARS-CoV-2 serology.
Perkmann T. et al, (2022), Journal of clinical pathology
Mortality risks associated with empirical antibiotic activity in Escherichia coli bacteraemia: an analysis of electronic health records
Yoon CH. et al, (2022), Journal of Antimicrobial Chemotherapy, 77, 2536 - 2545