Publications

Translesion Synthesis And Errorprone Polymerases

Green CM. and Lehmann AR., (2021), 199 - 223

Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses

Barrett JR. et al, (2021), Nature Medicine, 27, 279 - 288

T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial

Ewer KJ. et al, (2021), Nature Medicine, 27, 270 - 278

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

Voysey M. et al, (2021), The Lancet, 397, 99 - 111

Genomic Instability Is an Early Event in Aluminium-Induced Tumorigenesis.

Mandriota SJ. et al, (2020), International journal of molecular sciences, 21

Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial

Ramasamy MN. et al, (2020), The Lancet, 396, 1979 - 1993

Specific Mechanisms of Chromosomal Instability Indicate Therapeutic Sensitivities in High-Grade Serous Ovarian Carcinoma.

Tamura N. et al, (2020), Cancer research, 80, 4946 - 4959

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

Yeow ZY. et al, (2020), Nature, 585, 447 - 452

ZCWPW1 is recruited to recombination hotspots by PRDM9 and is essential for meiotic double strand break repair

Wells D. et al, (2020), eLife, 9

Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial

Folegatti PM. et al, (2020), The Lancet, 396, 467 - 478

The Configuration of RPA, RAD51, and DMC1 Binding in Meiosis Reveals the Nature of Critical Recombination Intermediates

Hinch AG. et al, (2020), Molecular Cell, 79, 689 - 701.e10

A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity.

Nelson L. et al, (2020), Nature communications, 11

CRISPR-Cas9 Causes Chromosomal Instability and Rearrangements in Cancer Cell Lines, Detectable by Cytogenetic Methods.

Rayner E. et al, (2019), The CRISPR journal, 2, 406 - 416

ZCWPW1 is recruited to recombination hotspots by PRDM9, and is essential for meiotic double strand break repair

Wells D. et al, (2019)

The RS4;11 cell line as a model for leukaemia with t(4;11)(q21;q23): Revised characterisation of cytogenetic features.

Ragusa D. et al, (2019), Cancer reports (Hoboken, N.J.), 2

Migration through physical constraints is enabled by MAPK-induced cell softening via actin cytoskeleton re-organization.

Rudzka DA. et al, (2019), Journal of cell science, 132

The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosome

Gdula MR. et al, (2019), Nature Communications, 10

The p38α Stress Kinase Suppresses Aneuploidy Tolerance by Inhibiting Hif-1α

Simões-Sousa S. et al, (2018), Cell Reports, 25, 749 - 760.e6

53BP1 cooperation with the REV7–shieldin complex underpins DNA structure-specific NHEJ

Ghezraoui H. et al, (2018), Nature, 560, 122 - 127

PCNA dependent cellular activities tolerate dramatic perturbations in PCNA client interactions

Wilson RHC. et al, (2017), DNA Repair, 50, 22 - 35

Repo-Man/PP1 regulates heterochromatin formation in interphase

de Castro IJ. et al, (2017), Nature Communications, 8

Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion

Singh MS. et al, (2016), Nature Communications, 7

Photoreceptor precursor transplantation leads to exchange of cellular contents between the donor and host retina

Barnard AR. et al, (2016), INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 57

Investigating cell fusion between the donor and host retina after photoreceptor precursor transplantation

Barnard A. et al, (2016), HUMAN GENE THERAPY, 27, A15 - A15

Abstract A29: Hypoxia regulated long noncoding RNAs and antisense transcripts in breast cancer: Novel insights of noncoding transcriptional regulation in hypoxic microenvironment

Choudhry H. et al, (2016), Cancer Research, 76, A29 - A29

Re-engineering the zinc fingers of PRDM9 reverses hybrid sterility in mice

Davies B. et al, (2016), Nature, 530, 171 - 176

Language impairment in a case of a complex chromosomal rearrangement with a breakpoint downstream of FOXP2

Moralli D. et al, (2015), Molecular Cytogenetics, 8

Erratum: Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival

Choudhry H. et al, (2015), Oncogene, 34, 4546 - 4546

Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival

Choudhry H. et al, (2015), Oncogene, 34, 4482 - 4490

A fluorescent bimolecular complementation screen reveals MAF1, RNF7 and SETD3 as PCNA-associated proteins in human cells

Cooper SE. et al, (2015), Cell Cycle, 14, 2509 - 2519

PCNA mutation affects DNA repair not replication

Green CM. et al, (2014), Cell Cycle, 13, 3157 - 3158

Hypomorphic PCNA mutation underlies a human DNA repair disorder

Baple EL. et al, (2014), Journal of Clinical Investigation, 124, 3137 - 3146

Spatial separation of Xist RNA and polycomb proteins revealed by superresolution microscopy

Cerase A. et al, (2014), Proceedings of the National Academy of Sciences, 111, 2235 - 2240

Purification and Analysis of Checkpoint Protein Complexes From <I>Saccharomyces cerevisiae</I>

Green CM. and Lowndes NF., (2013), 291 - 306

Regulation of translesion synthesis in human cells

Lehmann AR. et al, (2012), MUTAGENESIS, 27, 106 - 106

Maintenance of Silent Chromatin through Replication Requires SWI/SNF-like Chromatin Remodeler SMARCAD1

Rowbotham SP. et al, (2011), Molecular Cell, 42, 285 - 296

ATR-mediated phosphorylation of DNA polymerase η is needed for efficient recovery from UV damage

Göhler T. et al, (2011), Journal of Cell Biology, 192, 219 - 227

Ubiquitin-PCNA fusion as a mimic for mono-ubiquitinated PCNA in Schizosaccharomyces pombe

Ramasubramanyan S. et al, (2010), DNA Repair, 9, 777 - 784

Regulation of Translesion Synthesis DNA Polymerase η by Monoubiquitination

Bienko M. et al, (2010), Molecular Cell, 37, 396 - 407

Analysis of replication factories in human cells by super-resolution light microscopy

Cseresnyes Z. et al, (2009), BMC Cell Biology, 10

Ubiquitin-binding motif of human DNA polymerase η is required for correct localization

Sabbioneda S. et al, (2009), Proceedings of the National Academy of Sciences, 106

Effect of Proliferating Cell Nuclear Antigen Ubiquitination and Chromatin Structure on the Dynamic Properties of the Y-family DNA Polymerases

Sabbioneda S. et al, (2008), Molecular Biology of the Cell, 19, 5193 - 5202

Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells

Niimi A. et al, (2008), Proceedings of the National Academy of Sciences, 105, 16125 - 16130

Translesion synthesis: Y-family polymerases and the polymerase switch

LEHMANN A. et al, (2007), DNA Repair, 6, 891 - 899

One ring to rule them all? Another cellular responsibility for PCNA

Green CM., (2006), Trends in Molecular Medicine, 12, 455 - 458

Postreplication Repair and PCNA Modification inSchizosaccharomyces pombe

Frampton J. et al, (2006), Molecular Biology of the Cell, 17, 2976 - 2985

Multiple approaches to study S. cerevisiae Rad9, a prototypical checkpoint protein.

O'Shaughnessy AM. et al, (2006), 409, 131 - 150

Ubiquitin-Binding Domains in Y-Family Polymerases Regulate Translesion Synthesis

Bienko M. et al, (2005), Science, 310, 1821 - 1824

A Role for Polymerase η in the Cellular Tolerance to Cisplatin-Induced Damage

Albertella MR. et al, (2005), Cancer Research, 65, 9799 - 9806

Repairing DNA damage in chromatin

Gontijo A., (2003), Biochimie, 85, 1133 - 1147

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Publications