Design of vaccine efficacy trials during public health emergencies
Dean NE., Gsell P-S., Brookmeyer R., De Gruttola V., Donnelly CA., Halloran ME., Jasseh M., Nason M., Riveros X., Watson CH., Henao-Restrepo AM., Longini IM.
This Perspective describes key considerations for the design and analysis of candidate vaccine trials during public health emergencies.