Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses
Barrett JR. et al, (2021), Nature Medicine, 27, 279 - 288
T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial
Ewer KJ. et al, (2021), Nature Medicine, 27, 270 - 278
Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK
Voysey M. et al, (2021), The Lancet, 397, 99 - 111
Genomic Instability Is an Early Event in Aluminium-Induced Tumorigenesis.
Mandriota SJ. et al, (2020), International journal of molecular sciences, 21
Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial
Ramasamy MN. et al, (2020), The Lancet, 396, 1979 - 1993
Specific Mechanisms of Chromosomal Instability Indicate Therapeutic Sensitivities in High-Grade Serous Ovarian Carcinoma.
Tamura N. et al, (2020), Cancer research, 80, 4946 - 4959
Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.
Yeow ZY. et al, (2020), Nature, 585, 447 - 452
ZCWPW1 is recruited to recombination hotspots by PRDM9 and is essential for meiotic double strand break repair
Wells D. et al, (2020), eLife, 9
Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial
Folegatti PM. et al, (2020), The Lancet, 396, 467 - 478
The Configuration of RPA, RAD51, and DMC1 Binding in Meiosis Reveals the Nature of Critical Recombination Intermediates
Hinch AG. et al, (2020), Molecular Cell, 79, 689 - 701.e10
A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity.
Nelson L. et al, (2020), Nature communications, 11
CRISPR-Cas9 Causes Chromosomal Instability and Rearrangements in Cancer Cell Lines, Detectable by Cytogenetic Methods.
Rayner E. et al, (2019), The CRISPR journal, 2, 406 - 416
The RS4;11 cell line as a model for leukaemia with t(4;11)(q21;q23): Revised characterisation of cytogenetic features.
Ragusa D. et al, (2019), Cancer reports (Hoboken, N.J.), 2
Migration through physical constraints is enabled by MAPK-induced cell softening via actin cytoskeleton re-organization.
Rudzka DA. et al, (2019), Journal of cell science, 132
The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosome
Gdula MR. et al, (2019), Nature Communications, 10
The p38α Stress Kinase Suppresses Aneuploidy Tolerance by Inhibiting Hif-1α
Simões-Sousa S. et al, (2018), Cell Reports, 25, 749 - 760.e6
53BP1 cooperation with the REV7–shieldin complex underpins DNA structure-specific NHEJ
Ghezraoui H. et al, (2018), Nature, 560, 122 - 127
PCNA dependent cellular activities tolerate dramatic perturbations in PCNA client interactions
Wilson RHC. et al, (2017), DNA Repair, 50, 22 - 35
Repo-Man/PP1 regulates heterochromatin formation in interphase
de Castro IJ. et al, (2017), Nature Communications, 8
Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion
Singh MS. et al, (2016), Nature Communications, 7
Abstract A29: Hypoxia regulated long noncoding RNAs and antisense transcripts in breast cancer: Novel insights of noncoding transcriptional regulation in hypoxic microenvironment
Choudhry H. et al, (2016), Cancer Research, 76, A29 - A29
Re-engineering the zinc fingers of PRDM9 reverses hybrid sterility in mice
Davies B. et al, (2016), Nature, 530, 171 - 176
Investigating cell fusion between the donor and host retina after photoreceptor precursor transplantation
Barnard A. et al, (2016), HUMAN GENE THERAPY, 27, A15 - A15
Photoreceptor precursor transplantation leads to exchange of cellular contents between the donor and host retina
Barnard AR. et al, (2016), INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 57
Language impairment in a case of a complex chromosomal rearrangement with a breakpoint downstream of FOXP2
Moralli D. et al, (2015), Molecular Cytogenetics, 8
Erratum: Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival
Choudhry H. et al, (2015), Oncogene, 34, 4546 - 4546
Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival
Choudhry H. et al, (2015), Oncogene, 34, 4482 - 4490
A fluorescent bimolecular complementation screen reveals MAF1, RNF7 and SETD3 as PCNA-associated proteins in human cells
Cooper SE. et al, (2015), Cell Cycle, 14, 2509 - 2519
PCNA mutation affects DNA repair not replication
Green CM. et al, (2014), Cell Cycle, 13, 3157 - 3158
Hypomorphic PCNA mutation underlies a human DNA repair disorder
Baple EL. et al, (2014), Journal of Clinical Investigation, 124, 3137 - 3146
Spatial separation of Xist RNA and polycomb proteins revealed by superresolution microscopy
Cerase A. et al, (2014), Proceedings of the National Academy of Sciences, 111, 2235 - 2240
Purification and Analysis of Checkpoint Protein Complexes From <I>Saccharomyces cerevisiae</I>
Green CM. and Lowndes NF., (2013), 291 - 306
Regulation of translesion synthesis in human cells
Lehmann AR. et al, (2012), MUTAGENESIS, 27, 106 - 106
Maintenance of Silent Chromatin through Replication Requires SWI/SNF-like Chromatin Remodeler SMARCAD1
Rowbotham SP. et al, (2011), Molecular Cell, 42, 285 - 296
ATR-mediated phosphorylation of DNA polymerase η is needed for efficient recovery from UV damage
Göhler T. et al, (2011), Journal of Cell Biology, 192, 219 - 227
Ubiquitin-PCNA fusion as a mimic for mono-ubiquitinated PCNA in Schizosaccharomyces pombe
Ramasubramanyan S. et al, (2010), DNA Repair, 9, 777 - 784
Regulation of Translesion Synthesis DNA Polymerase η by Monoubiquitination
Bienko M. et al, (2010), Molecular Cell, 37, 396 - 407
Analysis of replication factories in human cells by super-resolution light microscopy
Cseresnyes Z. et al, (2009), BMC Cell Biology, 10
Ubiquitin-binding motif of human DNA polymerase η is required for correct localization
Sabbioneda S. et al, (2009), Proceedings of the National Academy of Sciences, 106
Effect of Proliferating Cell Nuclear Antigen Ubiquitination and Chromatin Structure on the Dynamic Properties of the Y-family DNA Polymerases
Sabbioneda S. et al, (2008), Molecular Biology of the Cell, 19, 5193 - 5202
Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells
Niimi A. et al, (2008), Proceedings of the National Academy of Sciences, 105, 16125 - 16130
Translesion synthesis: Y-family polymerases and the polymerase switch
LEHMANN A. et al, (2007), DNA Repair, 6, 891 - 899
One ring to rule them all? Another cellular responsibility for PCNA
Green CM., (2006), Trends in Molecular Medicine, 12, 455 - 458
Postreplication Repair and PCNA Modification inSchizosaccharomyces pombe
Frampton J. et al, (2006), Molecular Biology of the Cell, 17, 2976 - 2985
Multiple approaches to study S. cerevisiae Rad9, a prototypical checkpoint protein.
O'Shaughnessy AM. et al, (2006), 409, 131 - 150
Ubiquitin-Binding Domains in Y-Family Polymerases Regulate Translesion Synthesis
Bienko M. et al, (2005), Science, 310, 1821 - 1824
A Role for Polymerase η in the Cellular Tolerance to Cisplatin-Induced Damage
Albertella MR. et al, (2005), Cancer Research, 65, 9799 - 9806