Imaging real-time HIV-1 virion fusion with FRET-based biosensors

Jones DM., Padilla-Parra S.

AbstractWe have produced a novel, simple and rapid method utilising genetically encodable FRET-based biosensors to permit the detection of HIV-1 virion fusion in living cells. These biosensors show high sensitivity both spatially and temporally and allow the real-time recovery of HIV-1 fusion kinetics in both single cells and cell populations simultaneously.

DOI

10.1038/srep13449

Type

Journal article

Publisher

Springer Science and Business Media LLC

Publication Date

2015-08-24T00:00:00+00:00

Volume

5

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