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Search results (60)

« Back to Publications

TSC2/mTORC1 integrates deoxynivalenol signals recognized by membrane receptors IR and EGFR to restrict intestinal stem cell function

Dou C-X. et al, (2025), Journal of Hazardous Materials, 494, 138769 - 138769

Structural insights into Frizzled3 through nanobody modulators

Hillier J. et al, (2024), Nature Communications, 15

Cachd1 interacts with Wnt receptors and regulates neuronal asymmetry in the zebrafish brain

Powell GT. et al, (2024), Science, 384, 573 - 579

Switching of Receptor Binding Poses between Closely Related Enteroviruses

Zhou D. et al, (2022), Viruses, 14, 2625 - 2625

Structural Analysis and Development of Notum Fragment Screening Hits

Zhao Y. et al, (2022), ACS Chemical Neuroscience, 13, 2060 - 2077

Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit

Willis NJ. et al, (2022), Journal of Medicinal Chemistry, 65, 7212 - 7230

Cachd1 is a novel Frizzled- and LRP6-interacting protein required for neurons to acquire left-right asymmetric character

Powell GT. et al, (2022)

Virtual Screening Directly Identifies New Fragment-Sized Inhibitors of Carboxylesterase Notum with Nanomolar Activity

Steadman D. et al, (2022), Journal of Medicinal Chemistry, 65, 562 - 578

Structures and therapeutic potential of anti-RBD human monoclonal antibodies against SARS-CoV-2

Huang K-YA. et al, (2022), Theranostics, 12, 1 - 17

Structural Insights into Notum Covalent Inhibition

Zhao Y. et al, (2021), Journal of Medicinal Chemistry, 64, 11354 - 11363

Notum deacylates octanoylated ghrelin

Zhao Y. et al, (2021), Molecular Metabolism, 49, 101201 - 101201

Small-Molecule Inhibitors of Carboxylesterase Notum

Zhao Y. et al, (2021), Future Medicinal Chemistry, 13, 1001 - 1015

Neutralization potency of monoclonal antibodies recognizing dominant and subdominant epitopes on SARS-CoV-2 Spike is impacted by the B.1.1.7 variant.

Graham C. et al, (2021), Immunity, 54, 1276 - 1289.e6

Antibody evasion by the P.1 strain of SARS-CoV-2

Dejnirattisai W. et al, (2021), Cell, 184, 2939 - 2954.e9

Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine-induced sera

Zhou D. et al, (2021), Cell, 184, 2348 - 2361.e6

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