Jack Saunders
DPhil Student
I am a DPhil student working under Professor Teresa Lambe, based in the Oxford Vaccine Group. My research focuses on investigating the immune response in both humans and animals against emerging pathogens including Crimean-Congo haemorhagic fever virus (CCHFV) and other closely related bunyaviruses including Nairobi sheep disease virus (NSDV) to aid vaccine design. This works aims to develop and progress novel vaccines, and explores new assays to assess immunity and vaccine efficacy.
Prior to my PhD, I completed my undergraduate degree in Biochemistry at the University of Exeter. I then completed my Master's degree in Integrated Immunology at the University of Oxford, involving a research project that explored murine T-cell responses to Chlamydia trachomatis infection. I then worked at the Jenner Institute as a Research Assistant in the Emerging Pathogens Group on CCHFV and SARS-CoV-2 humoral responses.
Recent publications
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Adenoviral vectored vaccination protects against Crimean-Congo Haemorrhagic Fever disease in a lethal challenge model
Journal article
Saunders JE. et al, (2023), eBioMedicine, 90, 104523 - 104523
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An attenuated herpesvirus vectored vaccine candidate induces T-cell responses against highly conserved porcine reproductive and respiratory syndrome virus M and NSP5 proteins that are unable to control infection.
Journal article
de Brito RCF. et al, (2023), Frontiers in immunology, 14
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Development of anti-Crimean-Congo hemorrhagic fever virus Gc and NP-specific ELISA for detection of antibodies in domestic animal sera.
Journal article
Belij-Rammerstorfer S. et al, (2022), Frontiers in veterinary science, 9
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Reactogenicity and immunogenicity after a late second dose or a third dose of ChAdOx1 nCoV-19 in the UK: a substudy of two randomised controlled trials (COV001 and COV002)
Journal article
Flaxman A. et al, (2021), The Lancet, 398, 981 - 990
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The Integration of Human and Veterinary Studies for Better Understanding and Management of Crimean-Congo Haemorrhagic Fever
Journal article
Gilbride C. et al, (2021), Frontiers in Immunology, 12