Dr Lele Zhao
Postdoctoral Research Scientist
I am a researcher in Evolutionary Viral Genomics. I apply various methods, including genomics, phylogenetics, statistics and experimental evolution, to understand virus evolution and infectious diseases at different scales. The aim of my research is to find out what genomics data can tell us about the within-host evolution of viral pathogens, link these observations to between-host virus transmission patterns, and provide suggestions for clinical treatment and epidemic control measures.
Currently, my focus is on the within-host dynamics of HCV, and the HIV transmission interface.
After completing my PhD in Microbial Biology, supervised by Prof Siobain Duffy at Rutgers University (USA), I joined Prof Christophe Fraser's group (Pathogen Dynamics group, PSI-Oxford) as a postdoctoral researcher in March 2019. In January 2023, I started my second postdoc position with Prof Katrina Lythgoe (PSI/Biology-Oxford).
Recent publications
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The mutational spectrum of SARS-CoV-2 genomic and antigenomic RNA
Journal article
Zhao L. et al, (2022), Proceedings of the Royal Society B: Biological Sciences, 289
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Phylogenetic estimation of the viral fitness landscape of HIV-1 set-point viral load
Journal article
Zhao L. et al, (2022), Virus Evolution, 8
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Gauging genetic diversity of generalists: A test of genetic and ecological generalism with RNA virus experimental evolution.
Journal article
Zhao L. and Duffy S., (2019), Virus evolution, 5