Contact information
Victoria Fallon
victoria.fallon@well.ox.ac.uk
https://www.well.ox.ac.uk/research/research-groups/carroll-group
Miles Carroll
Director of the Research and Development Institute
Carroll Group: High Consequence Emerging Viruses Group
HOST-PATHOGEN INTERACTIONS OF HIGH CONSEQUENCE EMERGING VIRUSES
Our work centres around high consequence emerging viral infections. Currently, our focus is on Ebola, Lassa fever and SARS-CoV-2. We are interested in host-pathogen interactions, development of anti-virals and recently we have been looking at the IgG response following SARS-CoV-2 infection and/or vaccination in humans and animal models. To further support this work we are using a live virus neutralisation, multiplex immunoassays and novel ACE2 inhibition assay to inform on the ability of serum to neutralise SARS-CoV-2 variants of concern (VOC). We are also interested in the innate response to viral infection, particularly activation and/or evasion of the complement system
Recent publications
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Divergent trajectories of antiviral memory after SARS-CoV-2 infection
Journal article
Tomic A. et al, (2022), Nature Communications, 13
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Characterisation of SARS-CoV-2 genomic variation in response to molnupiravir treatment in the AGILE Phase IIa clinical trial.
Journal article
Donovan-Banfield I. et al, (2022), Nat Commun, 13
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An introduction to the Marburg virus vaccine consortium, MARVAC.
Journal article
Cross RW. et al, (2022), PLoS pathogens, 18
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Avatar Mice Underscore the Role of the T Cell-Dendritic Cell Crosstalk in Ebola Virus Disease and Reveal Mechanisms of Protection in Survivors.
Journal article
Rottstegge M. et al, (2022), Journal of virology
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Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model.
Journal article
Wing PAC. et al, (2022), PLoS pathogens, 18