Susan Morris
Dr
Senior Post-Doc Vaccine Development and Manufacturing
- Gilbert Group
Viral vector development and rapid manufacturing.
The main focus of my research is to generate Simian adenoviral vectored vaccines for a range of emerging and re-emerging pathogens including SARS CoV-2. Emerging pathogen outbreaks require a quick and efficient response. Manufacturing methods for Adenovirus vectors at large scale have been developed, however the process from selecting an antigen to starting a clinical trial can take at least 18 months. I have been working on improving the manufacturing processes for Adenovirus vaccines to minimise the time required from concept to end product. I am currently working on rapid analytical assays required during manufacturing. I work closely with the Clinical Biomanufacturing facility to ensure all processes are transferable to a GMP environment.
Another aspect of my research is the design and development of new viral vectors for various emerging pathogens. I am also interested in exploring novel vaccine delivery mechanisms.
Recent publications
Critical Path to First-in-Human Batches of ChAdOx Vectors, Including for Emergency Response
Journal article
Peralta Alvarez MP. et al, (2026), Vaccines, 14, 509 - 509
Rational Design of a Chimpanzee Adenoviral-Vector Vaccine Against Yellow Fever Through the Modification of Antigen Transmembrane Domains
Journal article
Ulaszewska M. et al, (2026), Vaccines, 14, 273 - 273
Development and Evaluation of Compact Semi-Synthetic Promoters for Enhanced Antigen Expression in Adenoviral-Vectored Vaccines
Journal article
Hlaváč M. et al, (2026), Vaccines, 14, 260 - 260
Heterologous mucosal vaccine boosting enhances mucosal and systemic immunity by distinct mechanisms.
Journal article
Bissett C. et al, (2026), The Journal of experimental medicine, 223
Immunization with matrix-, nucleoprotein and neuraminidase protects against H3N2 influenza challenge in pH1N1 pre-exposed pigs.
Journal article
Vatzia E. et al, (2023), NPJ vaccines, 8