Publications

An Interpretable Classification Model Using Gluten-Specific TCR Sequences Shows Diagnostic Potential in Coeliac Disease.

Fowler A. et al, (2023), Biomolecules, 13

Fine needle aspiration of human lymph nodes reveals cell populations and soluble interactors pivotal to immunological priming

Provine NM. et al, (2023)

Immune responses and clinical outcomes after COVID-19 vaccination in patients with liver disease and liver transplant recipients.

Murray SM. et al, (2023), Journal of hepatology

Single-cell analysis of human MAIT cell transcriptional, functional and clonal diversity

Garner LC. et al, (2023), Nature Immunology, 24, 1565 - 1578

Targeting MAIT cells as a cellular adjuvant for humoral immunity: a new player in a very old game.

Provine NM., (2023), Immunology and cell biology, 101, 470 - 472

Adenovirus vector and mRNA vaccines: Mechanisms regulating their immunogenicity.

Provine NM. and Klenerman P., (2023), European journal of immunology, 53

The HDAC inhibitor zabadinostat is a systemic regulator of adaptive immunity.

Liu G. et al, (2023), Communications biology, 6

A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice

Hackstein C-P. et al, (2022), Nature Communications, 13

A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice

Hackstein C-P. et al, (2022)

Fatal COVID-19 outcomes are associated with an antibody response targeting epitopes shared with endemic coronaviruses

McNaughton AL. et al, (2022), JCI Insight, 7

Adenovirus vectors activate Vδ2+ γδT cells in a type I interferon‐, TNF‐, and IL‐18‐dependent manner

Provine NM. et al, (2022), European Journal of Immunology, 52, 835 - 837

CMV-associated T cell and NK cell terminal differentiation does not affect immunogenicity of ChAdOx1 vaccination

Sharpe HR. et al, (2022), JCI Insight, 7

Human MAIT cells show clonal diversity but transcriptional and functional homogeneity

Garner LC. et al, (2022)

Evaluation of perturbed iron-homeostasis in a prospective cohort of patients with COVID-19

Frost J. et al, (2022)

Evaluation of perturbed iron-homeostasis in a prospective cohort of patients with COVID-19.

Frost JN. et al, (2022), Wellcome open research, 7

Identification of immune correlates of fatal outcomes in critically ill COVID-19 patients

Youngs J. et al, (2021), PLOS Pathogens, 17, e1009804 - e1009804

Adenovirus vector vaccination reprograms pulmonary fibroblastic niches to support protective inflating memory CD8+ T cells.

Cupovic J. et al, (2021), Nature immunology, 22, 1042 - 1051

Fatal COVID-19 outcomes are associated with an antibody response targeting epitopes shared with endemic coronaviruses

McNaughton AL. et al, (2021)

T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial

Ewer KJ. et al, (2021), Nature Medicine, 27, 270 - 278

MAIT cell activation augments adenovirus vector vaccine immunogenicity

Provine NM. et al, (2021), Science, 371, 521 - 526

Human intestinal tissue-resident memory T cells comprise transcriptionally and functionally distinct subsets

FitzPatrick MEB. et al, (2021), Cell Reports, 34, 108661 - 108661

Treatment of COVID-19 with remdesivir in the absence of humoral immunity: a case report.

Buckland MS. et al, (2020), Nature communications, 11

Successful treatment of COVID-19 with remdesivir in the absence of humoral immunity

Buckland MS. et al, (2020)

MAIT Cells in Health and Disease.

Provine NM. and Klenerman P., (2020), Annual review of immunology, 38, 203 - 228

Human MAIT Cell Activation In Vitro

Hagel JP. et al, (2020), 97 - 124

Activation of MAIT cells plays a critical role in viral vector vaccine immunogenicity

Provine NM. et al, (2019)

Combined HDAC and BET Inhibition Enhances Melanoma Vaccine Immunogenicity and Efficacy

Badamchi-Zadeh A. et al, (2018), The Journal of Immunology, 201, 2744 - 2752

Memory inflation following adenoviral vaccination depends on IL-21

Gordon CL. et al, (2018), Vaccine, 36, 7011 - 7016

Insights Into Mucosal-Associated Invariant T Cell Biology From Studies of Invariant Natural Killer T Cells

Garner LC. et al, (2018), Frontiers in Immunology, 9

Immunogenicity and Cross-Reactivity of Rhesus Adenoviral Vectors

Iampietro MJ. et al, (2018), Journal of Virology, 92

Unique and Common Features of Innate-Like Human Vδ2+ γδT Cells and Mucosal-Associated Invariant T Cells

Provine NM. et al, (2018), Frontiers in Immunology, 9

Novel Concepts for HIV Vaccine Vector Design

Alayo QA. et al, (2017), mSphere, 2

Combined HDAC and BET inhibition to enhance cancer vaccine-elicited T-cell responses.

Badamchi-Zadeh A. et al, (2017), Journal of Clinical Oncology, 35, e14632 - e14632

Development of novel replication-defective lymphocytic choriomeningitis virus vectors expressing SIV antigens

Penaloza MacMaster P. et al, (2017), Vaccine, 35, 1 - 9

Adenovirus serotype 5 vaccine vectors trigger IL-27–dependent inhibitory CD4 + T cell responses that impair CD8 + T cell function

Larocca RA. et al, (2016), Science Immunology, 1

Immediate Dysfunction of Vaccine-Elicited CD8+ T Cells Primed in the Absence of CD4+ T Cells

Provine NM. et al, (2016), The Journal of Immunology, 197, 1809 - 1822

Inhibitory receptor expression on memory CD8 T cells following Ad vector immunization

Penaloza-MacMaster P. et al, (2016), Vaccine, 34, 4955 - 4963

Adenovirus Serotype 5 Vectors Trigger IL-27-Dependent Inhibitory CD4(+) T Cell Responses

Larocca RA. et al, (2016), JOURNAL OF IMMUNOLOGY, 196

Transient CD4 + T Cell Depletion Results in Delayed Development of Functional Vaccine-Elicited Antibody Responses

Provine NM. et al, (2016), Journal of Virology, 90, 4278 - 4288

CD4 T Cell Depletion Substantially Augments the Rescue Potential of PD-L1 Blockade for Deeply Exhausted CD8 T Cells

Penaloza-MacMaster P. et al, (2015), The Journal of Immunology, 195, 1054 - 1063

Vaccine-elicited CD4 T cells induce immunopathology after chronic LCMV infection

Penaloza-MacMaster P. et al, (2015), Science, 347, 278 - 282

Hexon Hypervariable Region-Modified Adenovirus Type 5 (Ad5) Vectors Display Reduced Hepatotoxicity but Induce T Lymphocyte Phenotypes Similar to Ad5 Vectors

Teigler JE. et al, (2014), Clinical and Vaccine Immunology, 21, 1137 - 1144

Augmented Replicative Capacity of the Boosting Antigen Improves the Protective Efficacy of Heterologous Prime-Boost Vaccine Regimens

Penaloza-MacMaster P. et al, (2014), Journal of Virology, 88, 6243 - 6254

Longitudinal Requirement for CD4+ T Cell Help for Adenovirus Vector–Elicited CD8+ T Cell Responses

Provine NM. et al, (2014), The Journal of Immunology, 192, 5214 - 5225

Ad5 but Not Ad26 Induces an IFN-Gamma + IL-10+CD4+T Cell Population Following Immunization

Larocca RA. et al, (2013), AIDS RESEARCH AND HUMAN RETROVIRUSES, 29, A127 - A128

Memory CD4 T Cells Provide Help Following Acute Viral Challenge, but Promote Lethal Immunopathology Following Chronic Viral Challenge

Penaloza-MacMaster P. et al, (2013), AIDS RESEARCH AND HUMAN RETROVIRUSES, 29, A122 - A122

An Attenuated Listeria monocytogenes Vector Primes More Potent Simian Immunodeficiency Virus-Specific Mucosal Immunity than DNA Vaccines in Mice

Im E-J. et al, (2013), Journal of Virology, 87, 4751 - 4755

Alternative Serotype Adenovirus Vaccine Vectors Elicit Memory T Cells with Enhanced Anamnestic Capacity Compared to Ad5 Vectors

Penaloza-MacMaster P. et al, (2013), Journal of Virology, 87, 1373 - 1384

The neutralization sensitivity of viruses representing human immunodeficiency virus type 1 variants of diverse subtypes from early in infection is dependent on producer cell, as well as characteristics of the specific antibody and envelope variant

Provine NM. et al, (2012), Virology, 427, 25 - 33

The Infectious Molecular Clone and Pseudotyped Virus Models of Human Immunodeficiency Virus Type 1 Exhibit Significant Differences in Virion Composition with Only Moderate Differences in Infectivity and Inhibition Sensitivity

Provine NM. et al, (2009), Journal of Virology, 83, 9002 - 9007

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Publications