Multi-omics analysis reveals COVID-19 vaccine induced attenuation of inflammatory responses during breakthrough disease.
Journal article
Drury RE. et al, (2024), Nat Commun, 15
Typhoid conjugate vaccines: a step towards typhoid control
Journal article
Shakya M. and Pollard AJ., (2024), The Lancet Global Health, 12, e535 - e536
Targeted metagenomics reveals association between severity and pathogen co-detection in infants with respiratory syncytial virus
Journal article
Lin G-L. et al, (2024), Nature Communications, 15
Airway and Blood Monocyte Transcriptomic Profiling Reveals an Antiviral Phenotype in Infants With Severe Respiratory Syncytial Virus Infection.
Journal article
Chappin K. et al, (2024), The Journal of infectious diseases, 229, S100 - S111
Evaluating the relationship between ciprofloxacin prescription and non-susceptibility in Salmonella Typhi in Blantyre, Malawi: an observational study.
Journal article
Ashton PM. et al, (2024), The Lancet. Microbe, 5, e226 - e234
Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort study.
Journal article
Schlapbach LJ. et al, (2024), The Lancet. Child & adolescent health
Impact of Subgroup Distribution on Seasonality of Human Respiratory Syncytial Virus: A Global Systematic Analysis.
Journal article
Deng S. et al, (2024), The Journal of infectious diseases, 229, S25 - S33
Paediatric meningitis in the conjugate vaccine era and a novel clinical decision model to predict bacterial aetiology.
Journal article
Ng M. et al, (2024), The Journal of infection
Respiratory Syncytial Virus-Associated Hospital Admissions by Deprivation Levels Among Children and Adults in Scotland.
Journal article
Osei-Yeboah R. et al, (2024), The Journal of infectious diseases, 229, S61 - S69
Respiratory Syncytial Virus-Associated Hospitalization in Adults With Comorbidities in 2 European Countries: A Modeling Study.
Journal article
Osei-Yeboah R. et al, (2024), The Journal of infectious diseases, 229, S70 - S77
Underreporting and Misclassification of Respiratory Syncytial Virus-Coded Hospitalization Among Adults in Denmark Between 2015-2016 and 2017-2018.
Journal article
Egeskov-Cavling AM. et al, (2024), The Journal of infectious diseases, 229, S78 - S83
Implementation and Adherence to Regular Asymptomatic Testing in a COVID-19 Vaccine Trial
Preprint
Williams LR. et al, (2024)
Long-Term Clinical Safety of the Ad26.ZEBOV and MVA-BN-Filo Ebola Vaccines: A Prospective, Multi-Country, Observational Study
Journal article
Puri A. et al, (2024), Vaccines, 12, 210 - 210
AZD1222 effectiveness against severe COVID-19 in individuals with comorbidity or frailty: the RAVEN cohort study.
Journal article
Meeraus W. et al, (2024), The Journal of infection
Protocol for the challenge non-typhoidal Salmonella (CHANTS) study: a first-in-human, in-patient, double-blind, randomised, safety and dose-escalation controlled human infection model in the UK.
Journal article
Smith C. et al, (2024), BMJ open, 14
The safety and immunogenicity of a bivalent conjugate vaccine against Salmonella enterica Typhi and Paratyphi A in healthy Indian adults: a phase 1, randomised, active-controlled, double-blind trial
Journal article
Kulkarni PS. et al, (2024), The Lancet
Spotlight on systems vaccinology: a novel approach to elucidate correlates of protection.
Journal article
Zhu H. et al, (2023), Genes Immun
The collective voice of early phase COVID-19 vaccine trial participants: Insights for improving confidence in novel vaccines.
Journal article
Thomas TM. et al, (2023), Human vaccines & immunotherapeutics, 19
Salmonella Vaccine Study in Oxford (SALVO) trial: protocol for an observer-participant blind randomised placebo-controlled trial of the iNTS-GMMA vaccine within a European cohort.
Journal article
Hanumunthadu B. et al, (2023), BMJ Open, 13
Intravenous immunoglobulin treatment in childhood encephalitis (IgNiTE): a randomised controlled trial.
Journal article
Hill M. et al, (2023), BMJ Open, 13
A multi-platform approach to identify a blood-based host protein signature for distinguishing between bacterial and viral infections in febrile children (PERFORM): a multi-cohort machine learning study
Journal article
Jackson HR. et al, (2023), The Lancet. Digital health, 5, e774 - e785
Raising AWaRe-ness of antimicrobial stewardship challenges in pediatric emergency care: results from the PERFORM study assessing consistency and appropriateness of antibiotic prescribing across Europe.
Journal article
Kolberg L. et al, (2023), Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Early transcriptional responses to human enteric fever challenge
Journal article
Barton A. et al, (2023), Infection and Immunity
External validation of the discriminative validity of the ReSVinet score & development of simplified ReSVinet scores in secondary care.
Journal article
Sheikh Z. et al, (2023), The Journal of infectious diseases
Global diversity and antimicrobial resistance of typhoid fever pathogens: Insights from a meta-analysis of 13,000 Salmonella Typhi genomes.
Journal article
Carey ME. et al, (2023), eLife, 12
Immunogenicity and safety of AZD2816, a beta (B.1.351) variant COVID-19 vaccine, and AZD1222 (ChAdOx1 nCoV-19) as third-dose boosters for previously vaccinated adults: a multicentre, randomised, partly double-blinded, phase 2/3 non-inferiority immunobridging study in the UK and Poland.
Journal article
Ramasamy MN. et al, (2023), The Lancet. Microbe
Motivations for paediatric vaccine trial participation.
Journal article
Hillson K. et al, (2023), Trials, 24
Relationship between molecular pathogen detection and clinical disease in febrile children across Europe: a multicentre, prospective observational study
Journal article
Shah P. et al, (2023), The Lancet Regional Health - Europe, 32
The burden of antimicrobial resistance in the Americas in 2019: a cross-country systematic analysis
Journal article
Aguilar GR. et al, (2023), The Lancet Regional Health - Americas, 25, 100561 - 100561
Diagnosis of childhood febrile illness using a multi-class blood RNA molecular signature
Journal article
Habgood-Coote D. et al, (2023), Med
External validation of a multivariable prediction model for identification of pneumonia and other serious bacterial infections in febrile immunocompromised children.
Journal article
Martin AJ. et al, (2023), Archives of disease in childhood
Immunogenicity, safety and reactogenicity of heterologous (third dose) booster vaccination with a full or fractional dose of two different COVID-19 vaccines: A phase 4, single-blind, randomized controlled trial in adults.
Journal article
Costa Clemens SA. et al, (2023), Human vaccines & immunotherapeutics, 19
Impact of infection on proteome-wide glycosylation revealed by distinct signatures for bacterial and viral pathogens.
Journal article
Willems E. et al, (2023), iScience, 26
Molecular correlates of vaccine-induced protection against typhoid fever
Journal article
Zhu H. et al, (2023), Journal of Clinical Investigation
Biobanking and consenting to research: a qualitative thematic analysis of young people's perspectives in the North East of England.
Journal article
van der Velden FJS. et al, (2023), BMC medical ethics, 24
Identification of circulating monocytes as producers of tuberculosis disease biomarker C1q.
Journal article
Niewold P. et al, (2023), Scientific reports, 13
Immunogenicity and seroefficacy of 10-valent and 13-valent pneumococcal conjugate vaccines: a systematic review and network meta-analysis of individual participant data
Journal article
Feng S. et al, (2023), eClinicalMedicine, 61, 102073 - 102073
Memory-like innate response to booster vaccination with MF-59 adjuvanted influenza vaccine in children.
Journal article
Kazmin D. et al, (2023), NPJ vaccines, 8
Optimising DTwP-containing vaccine infant immunisation schedules (OptImms) - a protocol for two parallel, open-label, randomised controlled trials.
Journal article
Kelly S. et al, (2023), Trials, 24
An adenoviral-vectored vaccine confers seroprotection against capsular group B meningococcal disease.
Journal article
Dold C. et al, (2023), Science translational medicine, 15
ChAdOx1 nCoV-19 (AZD1222) vaccine-induced Fc receptor binding tracks with differential susceptibility to COVID-19.
Journal article
Kaplonek P. et al, (2023), Nature immunology
Diagnosis of Multisystem Inflammatory Syndrome in Children by a Whole-Blood Transcriptional Signature.
Journal article
Jackson HR. et al, (2023), Journal of the Pediatric Infectious Diseases Society, 12, 322 - 331
Emergency medical services utilisation among febrile children attending emergency departments across Europe: an observational multicentre study.
Journal article
Tan CD. et al, (2023), European journal of pediatrics
Accelerating clinical development of a live attenuated vaccine against Salmonella Paratyphi A (VASP): study protocol for an observer-participant-blind randomised control trial of a novel oral vaccine using a human challenge model of Salmonella Paratyphi A infection in healthy adult volunteers.
Journal article
McCann N. et al, (2023), BMJ open, 13
Adeno-associated virus 2 infection in children with non-A-E hepatitis.
Journal article
Ho A. et al, (2023), Nature, 617, 555 - 563
Efficacy of primary series AZD1222 (ChAdOx1 nCoV-19) vaccination against SARS-CoV-2 variants of concern: Final analysis of a randomized, placebo-controlled, phase 1b/2 study in South African adults (COV005).
Journal article
Koen AL. et al, (2023), Vaccine, 41, 3486 - 3492
Genomic investigations of unexplained acute hepatitis in children.
Journal article
Morfopoulou S. et al, (2023), Nature, 617, 564 - 573
Immunisation with purified Coxiella burnetii phase I lipopolysaccharide confers partial protection in mice independently of co-administered adenovirus vectored vaccines.
Journal article
Dold C. et al, (2023), Vaccine, 41, 3047 - 3057