Preclinical development of a stabilized RH5 virus-like particle vaccine that induces improved antimalarial antibodies.
King LDW. et al, (2024), Cell reports. Medicine, 5
Blood-stage malaria vaccine candidate RH5.1/Matrix-M in healthy Tanzanian adults and children; an open-label, non-randomised, first-in-human, single-centre, phase 1b trial
Silk SE. et al, (2024), The Lancet Infectious Diseases
Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies
Alanine DGW. et al, (2019), Cell, 178, 216 - 228.e21
Structural Basis for the Acceleration of Procollagen Processing by Procollagen C-Proteinase Enhancer-1
Pulido D. et al, (2018), Structure, 26, 1384 - 1392.e3
Positional scanning library applied to the human eosinophil cationic protein/RNase3 N-terminus reveals novel and potent anti-biofilm peptides
Pulido D. et al, (2018), European Journal of Medicinal Chemistry, 152, 590 - 599
Host Antimicrobial Peptides: The Promise of New Treatment Strategies against Tuberculosis
Arranz-Trullén J. et al, (2017), Frontiers in Immunology, 8
Structural similarities in the CPC clip motif explain peptide-binding promiscuity between glycosaminoglycans and lipopolysaccharides
Pulido D. et al, (2017), Journal of The Royal Society Interface, 14, 20170423 - 20170423
Crystal Structure of the Heterotrimeric Integrin-Binding Region of Laminin-111
Pulido D. et al, (2017), Structure, 25, 530 - 535
Crystallographic analysis of the laminin β2 short arm reveals how the LF domain is inserted into a regular array of LE domains
Pulido D. et al, (2017), Matrix Biology, 57-58, 204 - 212
Structural basis for endotoxin neutralization by the eosinophil cationic protein
Pulido D. et al, (2016), The FEBS Journal, 283, 4176 - 4191
A Novel RNase 3/ECP Peptide for Pseudomonas aeruginosa Biofilm Eradication That Combines Antimicrobial, Lipopolysaccharide Binding, and Cell-Agglutinating Activities
Pulido D. et al, (2016), Antimicrobial Agents and Chemotherapy, 60, 6313 - 6325
The first crystal structure of human RNase 6 reveals a novel substrate-binding and cleavage site arrangement
Prats-Ejarque G. et al, (2016), Biochemical Journal, 473, 1523 - 1536
Insights into the Antimicrobial Mechanism of Action of Human RNase6: Structural Determinants for Bacterial Cell Agglutination and Membrane Permeation
Pulido D. et al, (2016), International Journal of Molecular Sciences, 17, 552 - 552
Protein post‐translational modification in host defense: the antimicrobial mechanism of action of human eosinophil cationic protein native forms
Salazar VA. et al, (2014), The FEBS Journal, 281, 5432 - 5446
Ribonucleases as a host-defence family: evidence of evolutionarily conserved antimicrobial activity at the N-terminus
Torrent M. et al, (2013), Biochemical Journal, 456, 99 - 108
Towards the rational design of antimicrobial proteins
Pulido D. et al, (2013), The FEBS Journal, 280, 5841 - 5852
Two Human Host Defense Ribonucleases against Mycobacteria, the Eosinophil Cationic Protein (RNase 3) and RNase 7
Pulido D. et al, (2013), Antimicrobial Agents and Chemotherapy, 57, 3797 - 3805
Exploring New Biological Functions of Amyloids: Bacteria Cell Agglutination Mediated by Host Protein Aggregation
Torrent M. et al, (2012), PLoS Pathogens, 8, e1003005 - e1003005
Structural determinants of the eosinophil cationic protein antimicrobial activity
Boix E. et al, (2012), bchm, 393, 801 - 815
Antimicrobial Peptide Action on Parasites
Torrent M. et al, (2012), Current Drug Targets, 13, 1138 - 1147
The sulfate-binding site structure of the human eosinophil cationic protein as revealed by a new crystal form
Boix E. et al, (2012), Journal of Structural Biology, 179, 1 - 9
Antimicrobial Action and Cell Agglutination by the Eosinophil Cationic Protein Are Modulated by the Cell Wall Lipopolysaccharide Structure
Pulido D. et al, (2012), Antimicrobial Agents and Chemotherapy, 56, 2378 - 2385
AMPA: an automated web server for prediction of protein antimicrobial regions
Torrent M. et al, (2012), Bioinformatics, 28, 130 - 131
Lipopolysaccharide Neutralization by Antimicrobial Peptides: A Gambit in the Innate Host Defense Strategy
Pulido D. et al, (2012), Journal of Innate Immunity, 4, 327 - 336
Refining the Eosinophil Cationic Protein Antibacterial Pharmacophore by Rational Structure Minimization
Torrent M. et al, (2011), Journal of Medicinal Chemistry, 54, 5237 - 5244