High-resolution African HLA resource uncovers HLA-DRB1 expression effects underlying vaccine response.
Mentzer AJ. et al, (2024), Nature medicine
A systematic analysis of the human immune response to Plasmodium vivax
Bach FA. et al, (2023), Journal of Clinical Investigation
Human leukocyte antigen alleles associate with COVID-19 vaccine immunogenicity and risk of breakthrough infection
Mentzer AJ. et al, (2022), Nature Medicine
Controlled human malaria infection with a clone of Plasmodium vivax with high-quality genome assembly
Minassian AM. et al, (2021), JCI Insight, 6
Author Correction: Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses
Barrett JR. et al, (2021), Nature Medicine, 27, 1113 - 1113
Mapping immune variation and var gene switching in naive hosts infected with Plasmodium falciparum
Milne K. et al, (2021), eLife, 10
Publisher Correction: ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques
van Doremalen N. et al, (2021), Nature, 590, E24 - E24
Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses
Barrett JR. et al, (2021), Nature Medicine, 27, 279 - 288
ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques
van Doremalen N. et al, (2020), Nature, 586, 578 - 582
A single dose of ChAdOx1 MERS provides protective immunity in rhesus macaques
van Doremalen N. et al, (2020), Science Advances, 6
A defined mechanistic correlate of protection against Plasmodium falciparum malaria in non-human primates
Douglas AD. et al, (2019), Nature Communications, 10
Safety and Immunogenicity of a Novel Recombinant Simian Adenovirus ChAdOx2 as a Vectored Vaccine
Folegatti PM. et al, (2019), Vaccines, 7, 40 - 40
Safety and efficacy of novel malaria vaccine regimens of RTS,S/AS01B alone, or with concomitant ChAd63-MVA-vectored vaccines expressing ME-TRAP
Rampling T. et al, (2018), npj Vaccines, 3
Human vaccination against RH5 induces neutralizing antimalarial antibodies that inhibit RH5 invasion complex interactions
Payne RO. et al, (2017), JCI Insight, 2
SAFETY AND IMMUNOGENICITY OF THE NOVEL PLASMODIUM FALCIPARUM BLOOD-STAGE VACCINE CHAD63-MVA RH5 IN A PHASE IA CLINICAL TRIAL
Payne R. et al, (2017), AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 95, 313 - 313
Human vaccination against Plasmodium vivax Duffy-binding protein induces strain-transcending antibodies
Payne RO. et al, (2017), JCI Insight, 2
Viral Vector Malaria Vaccines Induce High-Level T Cell and Antibody Responses in West African Children and Infants
Bliss CM. et al, (2017), Molecular Therapy, 25, 547 - 559
Probability of Transmission of Malaria from Mosquito to Human Is Regulated by Mosquito Parasite Density in Naïve and Vaccinated Hosts
Churcher TS. et al, (2017), PLOS Pathogens, 13, e1006108 - e1006108
HIGH LEVEL EFFICACY IN HUMANS OF A NEXT-GENERATION PLASMODIUM FALCIPARUM ANTI-SPOROZOITE VACCINE: R21 IN MATRIX-M (TM) ADJUVANT
Venkatraman N. et al, (2017), AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 97, 594 - 594
PROBABILITY OF TRANSMISSION OF MALARIA FROM MOSQUITO TO HUMAN IS REGULATED BY PARASITE DENSITY IN NAIVE AND VACCINATED HOSTS
Churcher TS. et al, (2017), AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 97, 230 - 230
Safety, Immunogenicity and Efficacy of Prime-Boost Vaccination with ChAd63 and MVA Encoding ME-TRAP against Plasmodium falciparum Infection in Adults in Senegal
Mensah VA. et al, (2016), PLOS ONE, 11, e0167951 - e0167951
Safety and High Level Efficacy of the Combination Malaria Vaccine Regimen of RTS,S/AS01BWith Chimpanzee Adenovirus 63 and Modified Vaccinia Ankara Vectored Vaccines Expressing ME-TRAP
Rampling T. et al, (2016), Journal of Infectious Diseases, 214, 772 - 781
Demonstration of the Blood-StagePlasmodium falciparumControlled Human Malaria Infection Model to Assess Efficacy of theP. falciparumApical Membrane Antigen 1 Vaccine, FMP2.1/AS01
Payne RO. et al, (2016), Journal of Infectious Diseases, 213, 1743 - 1751
A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA
Ewer K. et al, (2016), New England Journal of Medicine, 374, 1635 - 1646
Increased sample volume and use of quantitative reverse-transcription PCR can improve prediction of liver-to-blood inoculum size in controlled human malaria infection studies
Hodgson SH. et al, (2015), Malaria Journal, 14
Assessment of FMP2.1/AS01B, an asexual blood-stage malaria vaccine, in a phase I/II a clinical trial using blood-stage controlled human malaria infection
Payne RO. et al, (2015), TROPICAL MEDICINE & INTERNATIONAL HEALTH, 20, 22 - 22
Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against Plasmodium falciparum infection in Kenyan adults
Ogwang C. et al, (2015), Science Translational Medicine, 7
Evaluation of the Efficacy of ChAd63-MVA Vectored Vaccines Expressing Circumsporozoite Protein and ME-TRAP Against Controlled Human Malaria Infection in Malaria-Naive Individuals
Hodgson SH. et al, (2015), Journal of Infectious Diseases, 211, 1076 - 1086
Translating the Immunogenicity of Prime-boost Immunization With ChAd63 and MVA ME-TRAP From Malaria Naive to Malaria-endemic Populations
Kimani D. et al, (2014), Molecular Therapy, 22, 1992 - 2003
Correction for Nébié et al., Assessment of Chimpanzee Adenovirus Serotype 63 Neutralizing Antibodies Prior to Evaluation of a Candidate Malaria Vaccine Regimen Based on Viral Vectors
Nébié I. et al, (2014), Clinical and Vaccine Immunology, 21, 1376 - 1376
Assessment of Chimpanzee Adenovirus Serotype 63 Neutralizing Antibodies Prior to Evaluation of a Candidate Malaria Vaccine Regimen Based on Viral Vectors
Nébié I. et al, (2014), Clinical and Vaccine Immunology, 21, 901 - 903
External Quality Assurance of Malaria Nucleic Acid Testing for Clinical Trials and Eradication Surveillance
Murphy SC. et al, (2014), PLoS ONE, 9, e97398 - e97398
Protective CD8+ T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation
Ewer KJ. et al, (2013), Nature Communications, 4
Comparison of Modeling Methods to Determine Liver-to-blood Inocula and Parasite Multiplication Rates During Controlled Human Malaria Infection
Douglas AD. et al, (2013), The Journal of Infectious Diseases, 208, 340 - 345
Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe
Sheehy SH. et al, (2013), PLoS ONE, 8, e65960 - e65960
Evaluation of the Safety and Immunogenicity of a Candidate Tuberculosis Vaccine, MVA85A, Delivered by Aerosol to the Lungs of Macaques
White AD. et al, (2013), Clinical and Vaccine Immunology, 20, 663 - 672
ChAd63-MVA–vectored Blood-stage Malaria Vaccines Targeting MSP1 and AMA1: Assessment of Efficacy Against Mosquito Bite Challenge in Humans
Sheehy SH. et al, (2012), Molecular Therapy, 20, 2355 - 2368
A Novel Chimpanzee Adenovirus Vector with Low Human Seroprevalence: Improved Systems for Vector Derivation and Comparative Immunogenicity
Dicks MDJ. et al, (2012), PLoS ONE, 7, e40385 - e40385
Comparison of Clinical and Parasitological Data from Controlled Human Malaria Infection Trials
Roestenberg M. et al, (2012), PLoS ONE, 7, e38434 - e38434
Clinical Assessment of a Recombinant Simian Adenovirus ChAd63: A Potent New Vaccine Vector
O’Hara GA. et al, (2012), The Journal of Infectious Diseases, 205, 772 - 781
Phase Ia Clinical Evaluation of the Safety and Immunogenicity of the Plasmodium falciparum Blood-Stage Antigen AMA1 in ChAd63 and MVA Vaccine Vectors
Sheehy SH. et al, (2012), PLoS ONE, 7, e31208 - e31208
ChAd63-MVA-vectored blood-stage Malaria vaccines targeting MSP1 and AMA1: Assessment of efficacy against mosquito bite challenge in humans
Sheehy SH. et al, (2012), Molecular Therapy, 20, 2355 - 2368
Impact on Malaria Parasite Multiplication Rates in Infected Volunteers of the Protein-in-Adjuvant Vaccine AMA1-C1/Alhydrogel+CPG 7909
Duncan CJA. et al, (2011), PLoS ONE, 6, e22271 - e22271
Cloning and characterization of hIF2, a human homologue of bacterial translation initiation factor 2, and its interaction with HIV-1 matrix
WILSON SA. et al, (1999), Biochemical Journal, 342, 97 - 97