Mahan Ghafari
Postdoctoral Research Scientist
I am mainly interested in understanding the evolutionary and epidemiological processes involved in determining the rate at which viruses evolve over time. In my current postdoctoral work, I study the within-host evolutionary dynamics, and transmission, of chronic viral infections such as SARS-CoV-2 and HIV. My focus is on analysing whole genome sequencing data to better understand the within-host evolution and transmission of these viruses, including the roles of selection, recombination, and compartmentalisation.
Recent publications
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Determinants of SARS-CoV-2 within-host evolutionary rates in persistently infected individuals
Ghafari M. et al, (2024)
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Revisiting the origins of the Sobemovirus genus: A case for ancient origins of plant viruses.
Ghafari M. et al, (2024), PLoS Pathog, 20
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Biased estimates of phylogenetic branch lengths resulting from the discretised Gamma model of site rate heterogeneity
Ferretti L. et al, (2024)
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A quantitative evaluation of the impact of vaccine roll-out rate and coverage on reducing deaths: insights from the first 2 years of COVID-19 epidemic in Iran.
Ghafari M. et al, (2023), BMC medicine, 21
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Lineage replacement and evolution captured by 3 years of the United Kingdom Coronavirus (COVID-19) Infection Survey
Lythgoe KA. et al, (2023), Proceedings of the Royal Society B: Biological Sciences, 290